Mesothelioma and Non Asbestos Exposure
Mesothelioma most commonly develops in the lining of the lungs (pleura) and abdomen (peritoneum). The rare cancer can also form in the tissue lining the heart (pericardium) or testes.
Asbestos exposure is a major risk factor for mesothelioma. However, some people diagnosed with mesothelioma don't have an asbestos-related history.
Exposure to Asbestos
Asbestos is a mineral that is natural that was once employed in industrial and construction products all over the world. Workers working in asbestos-related industries were exposed to asbestos on a daily basis. Asbestos fibers can get lodged in the lungs, which can cause lung diseases. This is called asbestosis. As time passes, these trapped fibers can also lead to mesothelioma. Asbestos fibers can be inhaled, eaten or absorbed through the skin. The risk of developing mesothelioma and other asbestos-related diseases rises when exposed.
Most cases of mesothelioma result from occupational exposure. Asbestos is a common ingredient in professions, including electrical work, and maintenance of automobiles. Since these occupations are predominantly male-dominated, 75-80% percent of mesothelioma is diagnosed in males. However, the gradual elimination of asbestos in the United States and other first-world countries has led to a decrease in exposure on the job. This has led to a shift of cases and non-occupational asbestos exposure increasing in frequency.
Non-occupational mesothelioma may occur when asbestos is released from the work environment or in the home or school environment. Exposure to asbestos from the outside can cause it, such as when a family member is exposed to the work clothes of a asbestos worker. This kind of exposure can cause symptoms like chest pain or a shortness of breathe that are often misinterpreted as heart conditions or lung conditions.
Certain studies have linked mesothelioma to non-occupational exposure, but the results are different. Many of these studies were conducted on a small sample size, and between-study heterogeneity has been high. More research is needed to establish the causality between mesothelioma and exposure to non-occupational substances.
People who have had non-occupational asbestos exposure should consult their doctor regarding their asbestos history. They should request mesothelioma testing when they are concerned, and ask for a referral to an expert. Mesothelioma specialists can provide patients with the best treatment and care options to improve their odds of survival. They will review medical records and perform imaging tests to identify mesothelioma. They will also give advice on how to file a mesothelioma suit to receive compensation from an asbestos trust fund.
Secondhand Exposure
While exposure to asbestos is the primary cause of mesothelioma not the only factor that can cause you to develop this disease. There is evidence that those who haven't been exposed to asbestos or worked in industries with asbestos-related activities can still develop mesothelioma. This is referred to as secondary or non-occupational asbestos exposure.
Asbestos fibres are very small and can adhere to hair, clothing, and skin. Workers can carry dangerous fibers in their work clothes at home, and then transfer them to family members. These stray asbestos fibers can be swallowed or inhaled, which can lead to mesothelioma.
The mesothelioma type is more prevalent in women, and usually occurs in the lungs. It can also affect the chest wall or abdomen. Shortness of breath is the most common indication. It can be associated with a range of other symptoms, including fluid in the lungs or swelling in the scrotum.
The mesothelioma that occurs in the lungs is known as mesothelioma pleural. Mesothelioma affecting the chest wall or stomach is known as peritoneal mesothelioma. This kind of mesothelioma may cause a number of symptoms including abdominal pain, difficulty in breathing and constipation.
Numerous studies have revealed that even those who have no prior previous history of exposure to asbestos can still get mesothelioma because of exposure to harmful fibers. Most often, these people have lived with someone who was exposed to the hazardous substance. They may have touched the worker's clothing, or they might have had other contact with asbestos.
Veterans are at risk of developing mesothelioma due to the widespread use of asbestos in military bases, ships and other vehicles. The Navy is at a higher risk since asbestos was used in the hull and gun turrets on ships to guard them from fire. Asbestos was also frequently taken home by sailors after their duties aboard ships that had been infected with asbestos.
Environmental Exposure
Mesothelioma is linked to a variety of materials. The disease is still most often linked to asbestos exposure. Asbestos, a naturally occurring mineral is used in the manufacture of products for a long time. It is resistant to heat and tough, which makes it ideal for insulation, brakes, shingles flooring, and many other products. Asbestos is broken down to dust that can be inhaled and swallowed. vermont asbestos attorneys may remain in the lungs or stomach for years, and trigger mesothelioma symptoms.
The most frequent symptoms of mesothelioma are chest pain, abdominal discomfort and difficulty breathing. Asbestos sufferers may experience these symptoms for 20 to 60 years or more following their initial exposure. It is essential to consult an expert physician if you experience these symptoms. Telling your doctor about asbestos exposure is essential. This can prevent a wrong diagnosis and ensure that you receive the right treatment.
The most common victims of mesothelioma from asbestos exposure are those who have worked directly with it but it is possible for loved family members to be affected. This is referred to as secondary exposure. Family members can take in asbestos fibers from a worker's footwear, clothing, or tools. They could also be exposed to asbestos by someone who brings home these particles on their clothing or hair. This is the reason mesothelioma sufferers and their families should always be sure to wash their clothing properly after working with asbestos.
There is a substantial amount of research that suggests a relationship between nonasbestos exposure and mesothelioma. However there is no conclusive evidence yet regarding the role played by other agents. For instance, there is some evidence that the zeolites erionite as well as chrysotile can cause mesothelioma. Erionite is found in the soil and in the rocks of certain areas of Turkey where mesothelioma occurrence rates are high.
Research on the relationship between mesothelioma and exposure to nonasbestos continues. Funnel plots have indicated the potential for bias in publications, and the between-study heterogeneity is high. It is evident that asbestos exposure is the most significant mesothelioma risk factor.
Genetics
Mesothelioma is a rare condition caused by malignant mesothelial cells which develop out of control and invade surrounding tissues. It is also able to spread throughout the body via the lymphatic or blood system, and affect other organs. While asbestos is the main cause of mesothelioma, it isn't the only risk factor. The condition can be caused by other genetic or environmental factors.
Some cases of mesothelioma have been reported in people who did not directly expose themselves to asbestos. They are known as non-occupational mesothelioma patients. They were usually exposed indirectly by the handling of contaminated clothing or household items by anyone who was exposed to asbestos in their home. For instance, it's possible for one to be diagnosed with pleural mesothelioma due to the inhalation of asbestos fibers from clothing belonging to a loved ones. Studies have shown that these kinds of mesothelioma cases tend to have longer latency times and are more likely to be diagnosed in wives rather than husbands.
Scientists are currently studying the possibility that mesothelioma's genetic susceptibility could play a role in the development of the disease. Recent studies have revealed that the mutation of a gene called BAP1 can increase the risk of mesothelioma among those who are exposed to asbestos. This finding is significant as it could lead to improved screening procedures for people who are at high risk of developing mesothelioma.
Researchers have discovered that a number of genes are associated with mesothelioma. These genes are often mutated in mesothelioma, and they suppress tumor growth. These genes include the large tumor suppressor homolog 2 (LATS2) and the NF2.
People who have mesothelioma in their family are at an increased risk for the cancer. This is due to the fact that certain genes, such as the BAP1, can be inherited from the parents. Asbestos was used heavily in the military for a number of years and veterans suffer from the highest rates of mesothelioma when compared to other occupational categories. People who worked on ships and in the Navy were at highest risk because of asbestos exposure in the construction of ships, insulation and fireproofing materials.